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KMID : 0363320140350010050
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Journal of Korean Oriental Internal Medicine
2014 Volume.35 No. 1 p.50 ~ p.58
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Correlation between Post-Stroke Depression and Cold, Heat, Deficiency and Excess Patterns
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Lee Il-Suk
Park Kee-Eon
Hong Hae-Jin
Song In-Ja
Sung Kang-Keyng
Lee Sang-Gwan
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Abstract
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Objectives : The aim of this study was to analyze relationship between post-stroke depression (PSD) and cold, heat, deficiency and excess patterns.
Methods : Twenty-eight PSD patients were recruited from STROKE center and measured with questionnaires for cold, heat, deficiency and excess patternvalues and saliva for cortisol awakening response (CAR). Saliva samples were collected immediately, 15, 30 and 45 min after awakening. In addition, Beck Depression Inventory (BDI) and Hamilton Depression Rating Scale (HDRS) were conducted for PSD severity. We conducted correlation analysis to find the relationship between cold, heat, deficiency and excess patterns and CAR or BDI and HDRS.
Results : Deficiency and excess patterns werepositively correlated with area under the curve with respect to the increase (AUCi), but not with area under the curve with respect to the global (AUCg), in CAR. Furthermore, it was negatively correlated with BDI and HDRS, while cold and heat patterns were not correlated with CAR, BDI and HDRS.
Conclusions : In terms of deficiency and excess patterns, the higher the PSD severity, the higher the deficiency and the lower the PSD severity, the higher the excess. However, there was not a significant relationship between PSD and cold and heat patterns.
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KEYWORD
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Post-stroke depression, cortisol awakening response, deficiency and excess, cold and heat patterns
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